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The Detection Assay Compound

SLU-PP-332

Also known as Pan-ERR agonist · Exercise mimetic

Summary coverage

At a glance

What it is
Pan-ERR agonist with no human programme. Its 2026 literature is doping detection.
Evidence
Practitioner experience onlyHow the tiers workSLU-PP-332 is confirmed as a small molecule, PubChem CID 5338394, formula C18H14N2O2, and is not a peptide. Why this tier
Half-life
Not established in available literature
Routes
Oral, Subcutaneous
Category
Metabolic
FDA
Not nominated
As of 3 August 2026. What that means
WADA
We do not state a status

Not schedulable in Claritide. Our sources publish no dosing figure for SLU-PP-332, so there is nothing to build a schedule from.

Evidence

Why this tier

SLU-PP-332 is confirmed as a small molecule, PubChem CID 5338394, formula C18H14N2O2, and is not a peptide. There is no human clinical trial programme and no human exposure data. The entire 2026 literature on it is anti-doping metabolite characterisation, with 22 in vitro metabolites identified and papers framed explicitly for doping-control purposes, plus structure-activity optimisation work and an orally active successor compound, SLU-PP-915. No credible human dose exists and we refuse to publish one.

Overview

What it is

SLU-PP-332 is a small-molecule agonist of the oestrogen-related receptors ERR-alpha, ERR-beta and ERR-gamma, from the Burris laboratory. There is no human clinical trial programme. Its entire 2026 literature is anti-doping metabolite characterisation and medicinal-chemistry optimisation, which tells you that the people paying attention to it professionally are the ones building tests to catch it.

Mechanism

How it works

The oestrogen-related receptors are transcription factors that govern mitochondrial biogenesis and fatty-acid oxidation, much of the transcriptional programme that endurance exercise switches on. SLU-PP-332 activates all three, which is why it is described as an exercise mimetic. The honest framing of that phrase, from the literature itself: it replicates the metabolic signalling of endurance training and does not replicate the mechanical stress of physical movement. Bone loading, tendon adaptation, cardiovascular work and the neuromuscular component of training are not in the package.

Dosing

Commonly researched ranges

These are figures reported in published literature and practitioner protocols: a commonly researched range, not a recommendation. Claritide does not tell you what to take.

Not established in available literature. Our sources describe SLU-PP-332 without publishing a dosing figure, so Claritide does not print one.

Cycle guidance
Not established in available literature
Goals
Fat loss, Energy
Legal standing

Where this sits with the FDA

Dated, sourced, and separate from whether it works. Removal from a warning list is not permission to compound.
Not nominatedas of 3 August 2026 · US

A preclinical research compound with no human clinical programme, no approval anywhere, and no entry on FDA’s compounding lists.

Primary source
Sport

WADA status

The 2026 Prohibited List entered force on 1 January 2026.
We do not state a status

We could not verify a WADA classification for SLU-PP-332 and do not state one. What is verified is that anti-doping laboratories are actively building detection assays for it: 22 in vitro metabolites have been characterised in papers framed explicitly for doping-control purposes. Draw the obvious inference about where this is heading, but we will not print a status we cannot source.

We looked and could not resolve it. This is not the same as "not prohibited". Treat it as unresolved and check with your federation before competing.

Reconstitution

Mixing recipes our sources document

Concentration (mg/mL) = vial mg ÷ diluent mL. On a U-100 barrel, 1 unit = 0.01 mL.

Not established in available literature. Use the calculator with the figures printed on your own vial.
Open the calculator

Expectations

Week by week

What our material describes people reporting. Individual responses vary widely.

Not established in available literature.

Tolerability

Side effects

Grouped by how often our sources report them. Percentages appear only where a published trial figure exists.

Not established in available literature. Absence from this page does not mean absence of risk. It means our sources publish no side-effect profile for SLU-PP-332.

Safety

Contraindications and interactions

Do not use if

  • No credible human dose exists, so there is no way to use this compound at a dose anyone has justified

Interactions

Not established in available literature.

Absence from this list does NOT mean safety. It means lack of research.

Handling

Storage and cost

Storage
Our sources publish no handling protocol, because there is no human dosing protocol to handle it for.
Cost
Not established in available literature
Deep dive

SLU-PP-332 in full

Limited coverage

SLU-PP-332 is a small molecule, PubChem CID 5338394, formula C18H14N2O2, and not a peptide. It is a potent selective agonist of the oestrogen-related receptors ERR-alpha, ERR-beta and ERR-gamma, developed in the Burris laboratory.

What it does, and what "exercise mimetic" actually means

The ERRs are transcription factors controlling mitochondrial biogenesis and fatty-acid oxidation, a large part of the programme endurance training switches on. Activating all three drives that programme pharmacologically.

The literature's own framing is the honest one: it replicates the metabolic signalling of endurance training, but does not replicate the mechanical stress of physical movement. No bone loading, no tendon adaptation, no cardiovascular work, no neuromuscular component. Whatever "exercise in a pill" means, it does not mean exercise.

No human programme

There is no human clinical trial programme and no human exposure data. None.

What there is, in 2026, is anti-doping chemistry. Twenty-two in vitro metabolites have been characterised, in papers framed explicitly for doping-control purposes and describing the compound as having doping potential. There is also medicinal-chemistry optimisation work and an orally active successor compound, SLU-PP-915.

That is a striking asymmetry. The only groups publishing on this molecule in 2026 are the ones designing tests to detect it in athletes, and the ones designing a better version of it. Neither is running a trial in people.

What we will not publish

A dose. There is no credible human dose for SLU-PP-332 and inventing one from a mouse study would be exactly the failure mode this library exists to avoid.

We also do not state a WADA classification, because we could not verify one. What we can say is that laboratories are actively building assays for it, which is not a status but is a fact worth knowing if you are tested.

References

Sources

  1. 1
    PubChem · SLU-PP-332, CID 5338394
  2. 2
    Anti-doping metabolite characterisation of SLU-PP-332 (2026)
  3. 3
    Further SLU-PP-332 doping-control chemistry (2026)
  4. 4
    Structure-activity optimisation and SLU-PP-915 (2026)

Every record in this library is free to read, and it stays free. Your own schedule, vials and log live in the app: Claritide for iPhone.